BDBM50280749 CHEMBL4169454

SMILES Cn1cc(\C=C2/CC(CO)(COC(=O)C(C)(C)C)OC2=O)c2ccccc12

InChI Key InChIKey=NMSQMKXWQOPPRS-NTEUORMPSA-N

Data  3 KI  15 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280749   

TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  970nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in human LNCAP cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  3.73E+3nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in human LNCAP cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  4.88E+3nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in HEK293 cells assessed as ERK1/2 phosphorylation after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAS guanyl-releasing protein 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50280749(CHEMBL4169454)
Affinity DataEC50:  860nMAssay Description:Activation of GFP-tagged RasGRP1 (unknown origin) expressed in HEK293 cells after 30 mins by immunoblot methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed